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KMID : 0191120100250091372
Journal of Korean Medical Science
2010 Volume.25 No. 9 p.1372 ~ p.1374
Acute Kidney Injury due to Menstruation-related Disseminated Intravascular Coagulation in an Adenomyosis Patient
Son Jung-Min

Kang Jin
Song Sang-Heon
Lee Dong-Won
Lee Soo-Bong
Kwak Ihm-Soo
Yang Byeong-Yun
Lee Kyu-Sup
Seong Eun-Young
Lee Su-Jin
Choi Jong-Ryeol
Abstract
The authors report a case of acute kidney injury (AKI) resulting from menstruation-related disseminated intravascular coagulation (DIC) in an adenomyosis patient. A 40-yr-old woman who had received gonadotropin for ovulation induction therapy presented with anuria and an elevated serum creatinine level. Her medical history showed primary infertility with diffuse adenomyosis. On admission, her pregnancy test was negative and her menstrual cycle had started 1 day previously. Laboratory data were consistent with DIC, and it was believed to be related to myometrial injury resulting from heavy intramyometrial menstrual flow. Gonadotropin is considered to play an important role in the development of fulminant DIC. This rare case suggests that physicians should be aware that gonadotropin may provoke fulminant DIC in women with adenomyosis.
KEYWORD
Kidney Failure, Multiple Organ Failure, Disseminated Intravascular Coagulation, Menstruation, Gonadotropins
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